Antiestrogen Series

Anastrozole (Arimidex)

Anti Estrogen Steroids Arimidex Anastrozole

Anastrozole Details

CAS: 120511-73-1
MF: C17H19N5
MW: 293.37
Purity: 99.8%
Standard: USP32
Appearance: White crystalline powder
Categories: Antineoplastic; All Inhibitors; Anti-neoplastic; Inhibitors; Intermediates & Fine Chemicals; Pharmaceuticals; Anastrozole; API
Usage: Anastrozole / Arimidex is not a steroid, but it is used during very high androgenic steroids such as Dianabol and testosterone where estrogen levels need to be watched because of gynecomastia and water retention purposes.

Anastrozole Description

Anastrozole Arimidex is a non-steroidal drug which is used to treat breast cancer. It has been thoroughly studied in women with breast cancer between the 5th-8th decades of life. There are some breast cancers which are dependent on estrogen for their growth. Arimidex acts by suppressing the levels of estrogen in the body and thus reduces the growth of breast cancer. The drug is first line treatment in post menopausal women with early breast cancer or in those with advanced breast cancer despite taking tamoxifen. Arimidex is often combined with other drugs to treat breast cancer in post menopausal women. The drug has been used to treat early or advanced breast cancer in women all cultures and races.

Anastrozole COA

Product Name Anastrozole
Production Bath 20170512 Production Date 2017-05-12
Specification USP 32 Shelf life 2 Years
Quantity 100kg Analysis Date 2017-05-12
Result For Analysis
Items Standard Results
Description White crystalline powder Complies
Identification IR
Conform with standard IR
Conform with standard HPLC
Solubility Freely soluble in methanol,acetone,
ethanol and tetrahydrofuran.
And very soluble in acetonitrile
Total Impurity Max.0.5% 0.18%
Total Unspecified Impurity Max. 0.2% 0.08%
Individual unspecified impurlty Max. 0.1% 0.05%
Related compound B Max. 0.2% 0.07%
Related compound C Max. 0.2% 0.04%
Related compound D Max. 0.1% 0.05%
Related compound E Max. 0.1% 0.06%
Limit of cyclohexane Max. 0.08% ND
Limit of ethylacetate Max. 0.1% 0.07%
Melting point 81.0~84.0ºC 82.5~83.2ºC
Water Max. 0.3% 0.21%
Residue on ignition Max. 0.1% 0.07%
Heavy Metals Max.0.001% Complies
Assay(HPLC) 98.0%~102.0% 99.8%
Conclusion This batch is complies with USP 32.

Anastrozole 4

Anastrozole Application

Anastrozole has been tested for reducing estrogens, including estradiol, in men. Excess estradiol in men can cause benign prostatic hyperplasia, gynecomastia, and symptoms of hypogonadism. It can also contribute to increased risk of stroke, heart attack, chronic inflammation, prostate enlargement and prostate cancer. Some athletes and body builders use anastrozole as part of their steroid cycle to reduce and prevent symptoms of excess estrogen–gynecomastia, emotional lability and water retention. Study data suggest dosages of 0.5 mg to 1 mg a day reduce serum estradiol by approximately 50% in men, which differs in postmenopausal women.

Anastrozole may be used off-label in children with precocious puberty, or children with pubertal gynecomastia. Following the onset of puberty, the epiphyseal plate begins to close due to an increased amount of estrogen production escaping local metabolism and spreading to the circulatory system. It is shown to help slow this process, and increase adult height prediction in adolescent males treated with protein-based peptide hormones for the treatment of growth hormone deficiency.

Anastrozole Usage

Take this medication by mouth with or without food, usually once a day, or as directed by your doctor. Use this medication regularly in order to get the most benefit from it. Remember to use it at the same time each day.

Do not increase your dose or take this medication more often without your doctor’s approval. Your condition will not improve any faster and the risk of serious side effects may be increased. Since this drug can be absorbed through the skin, women who are pregnant or who may become pregnant should not handle or break the tablets of this medication.

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