Bodybuilding Supplement Polypeptide Follistatin 344 / FST 344
Follistatin 344 Details
Name: Follistatin 344
Synonyms: FST, FS, Activin-binding protein
Appearance: Sterile Filtered White Lyophilized (Freeze-Dried)
Purity(by HPLC): >99.00%~99.90%
Total Impurities(by HPLC): 1.00%~0.05%
Single Impurity(by HPLC): <0.50%~0.08%
Physical Appearance: Sterile Filtered White lyophilized (freeze-dried) powder
Formulation:Lyophilized from a concentrated (1mg/ml) solution containing no additives.
Solubility: It is recommended to reconstitute the lyophilized Follistatin in sterile 18MΩ-cm H2O not less
than 100µg/ml, which can then be further diluted to other aqueous solutions.
Purity: Greater than 95.0% as determined by(a) Analysis by RP-HPLC.(b) Analysis by SDS-PAGE.
Storage Conditions:Aviod Shunshine and Keeping Stoppered
Follistatin 344 Stability: Lyophilized Follistatin although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution FST should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
Follistatin 344 Description
Follistatin is fascinating protein that can increase muscle mass beyond natural potential by suppressing myostatin. Scientists first identified follistatin while examining porcine (re: pig) follicular fluid in the ovaries.
Follistatin is naturally found in the skeletal muscle of almost all mammals with advanced or developed characteristics, such as humans, rodents, and cows. Follistatin is high in the non-essential amino acid cystine but unlike most proteins discussed in the fitness world, follistatin has carbohydrates attached to it.
Follistatin, specifically Follistatin 344 (FS344), quickly gained popularity in the bodybuilding community as a potential supplement to rapidly increase lean tissue mass. Another protein, follistatin-related gene (FLRG) acts on similar pathways as FS344 regarding its muscle building properties. Increased lean tissue mass could give a bodybuilder an advantage in a competitive setting and be the differentiating factor between first and second place.
Follistatin and Muscle Growth
Follistatin works by binding to and inhibiting transforming growth factor-β (TGF-β) peptides such as myostatin which is responsible for regulating and limiting muscle growth. It’s also worth pointing out that myostatin may have a regulatory role in skeletal muscle fibrosis; too much myostatin can impair tissue function and cause chronic disease in vital organs, tissues, and bone marrow.
FST(Recombinant Human Follistatin): Period in infants and children, continued growth of muscle, hardly any myostatin. However, as people move towards adulthood, the number of stabilizing muscles, myostatin to come into play. Scientists have found, named follistatin (follistatin) to the same protein myostatin sticking together, blocking its inhibitory function, and promote the growth of muscle fibers. Follistatin promote muscle growth due to the unique mechanism of action, FST joint use of steroids, IGF has better results. It only acts on muscle tissue , after use will not cause the proliferation of other tissue cells.